Monday, October 24, 2011

Pig-to-Human Transplants Could Be Closer Than You Think

Hog head, the deadliest food at the banquet 
fiskfisk, via

PopSci - Two scientists at the Thomas E. Starzl Transplantation Institute at the University of Pittsburgh discussed the state of xenotransplantation–the use of cells, organs, or tissue from one animal in another–in a review in The Lancet. In that review, they touch on the history of one particular subject: pig-to-human transplants. Their conclusion? Clinical trials of pig-to-human transplants could begin in just a few years.

Pigs that are genetically modified with genes to protect their organs and other inside bits from attack by the human immune system are capable of all kinds of potentially life-saving effects.

Research has been conducted until now with non-human primates, and while these primates have not been able to survive for all that long with pig organs–at best, a pig heart-implanted primate survives for around eight months–that could be enough time to serve as temporary lifesavers. Cells and tissue could be used to counteract human diseases like diabetes (as in this example) and Parkinson’s, and have actually shown more success than complete organs.